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A Ledda Selected Research

pycnogenols

9/2017Management of Varicose Veins and Chronic Venous Insufficiency in a Comparative Registry with Nine Venoactive Products in Comparison with Stockings.
2/2014Pycnogenol® in postpartum symptomatic hemorrhoids.
2/2014Pycnogenol® and Centella Asiatica for asymptomatic atherosclerosis progression.
12/2013Evaluation of the effects of supplementation with Pycnogenol® on fitness in normal subjects with the Army Physical Fitness Test and in performances of athletes in the 100-minute triathlon.
9/2010Improvement of signs and symptoms of chronic venous insufficiency and microangiopathy with Pycnogenol: a prospective, controlled study.
10/2008Jet-lag: prevention with Pycnogenol. Preliminary report: evaluation in healthy individuals and in hypertensive patients.
9/2008Pycnogenol may alleviate adverse effects in oncologic treatment.
4/2008Treatment of osteoarthritis with Pycnogenol. The SVOS (San Valentino Osteo-arthrosis Study). Evaluation of signs, symptoms, physical performance and vascular aspects.
1/2008Variations in C-reactive protein, plasma free radicals and fibrinogen values in patients with osteoarthritis treated with Pycnogenol.
10/2006Rapid relief of signs/symptoms in chronic venous microangiopathy with pycnogenol: a prospective, controlled study.
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A Ledda Research Topics

Disease

14Edema (Dropsy)
09/2017 - 03/2005
8Pain (Aches)
10/2016 - 08/2000
7Venous Insufficiency
09/2010 - 03/2005
6Hypertension (High Blood Pressure)
09/2011 - 08/2000
5Thrombosis (Thrombus)
09/2011 - 04/2007
4Osteoarthritis
01/2018 - 01/2008
4Venous Thrombosis (Deep-Vein Thrombosis)
01/2018 - 09/2008
4Atherosclerosis
04/2015 - 01/2000
4Diabetic Angiopathies (Diabetic Angiopathy)
12/2012 - 05/2006
4Ulcer
09/2011 - 11/2005
4Varicose Ulcer (Ulcer, Venous)
09/2011 - 11/2005
3Intermittent Claudication
08/2012 - 08/2000
3Infections
09/2011 - 04/2007
3Wounds and Injuries (Trauma)
09/2011 - 11/2005
3Vascular Diseases (Vascular Disease)
10/2008 - 08/2000
2Hematoma
10/2016 - 11/2005
2Fatigue
06/2015 - 10/2008
2Inflammation (Inflammations)
01/2014 - 09/2011
2Muscle Cramp (Cramp)
12/2013 - 05/2006
2Hypothyroidism
09/2011 - 09/2011
2Varicose Veins (Varicose Vein)
09/2011 - 09/2011
2Ankle Injuries (Ankle Injury)
10/2008 - 11/2005
2Thalassemia
01/2006 - 12/2005
1Insulin Resistance
10/2020
1Bacterial Infections (Bacterial Infection)
12/2017
1Febrile Neutropenia
12/2017
1Hemolytic Anemia
12/2017
1Neutropenia
12/2017
1Hematologic Neoplasms (Hematological Malignancy)
12/2017
1Glucosephosphate Dehydrogenase Deficiency
12/2017
1Urogenital Neoplasms
09/2017
1Neoplasms (Cancer)
09/2017
1Liver Diseases (Liver Disease)
06/2015
1Liver Failure
12/2014
1Hemorrhoids
02/2014
1Multiple Myeloma
11/2013
1Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
12/2012
1Dermatitis
09/2011
1Leprosy (Hansen's Disease)
09/2011
1Cicatrix (Scar)
09/2011
1Asthma (Bronchial Asthma)
09/2011
1Fever (Fevers)
09/2011
1Amenorrhea
09/2011
1Atopic Dermatitis (Atopic Eczema)
09/2011
1Psoriasis (Pustulosis Palmaris et Plantaris)
09/2011
1Lipodermatosclerosis
09/2011
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
11/2008

Drug/Important Bio-Agent (IBA)

15pycnogenolsIBA
09/2017 - 11/2005
7CurcuminIBA
01/2018 - 06/2010
4Heparin (Liquaemin)FDA LinkGeneric
09/2011 - 11/2005
3Insulin (Novolin)FDA Link
10/2020 - 11/2001
3TECAIBA
04/2015 - 09/2011
3AntioxidantsIBA
01/2014 - 01/2008
3Alprostadil (Muse)FDA LinkGeneric
08/2012 - 08/2000
3troxerutinIBA
06/2010 - 03/2005
2AnticoagulantsIBA
01/2018 - 04/2007
2Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
01/2018 - 09/2015
2LecithinsIBA
10/2016 - 01/2014
2Phospholipids (Phosphatides)FDA LinkGeneric
12/2012 - 06/2010
2disilver oxideIBA
09/2011 - 06/2010
2Ointments (Pastes)IBA
09/2011 - 06/2010
2Thyroxine (Levothyroxine)FDA LinkGeneric
09/2011 - 09/2011
2Oxygen (Dioxygen)IBA
09/2011 - 11/2005
2HesperidinIBA
04/2006 - 03/2006
2Diosmin (Daflon)IBA
04/2006 - 03/2006
2Prostaglandins EIBA
08/2000 - 08/2000
1Thyroid HormonesIBA
01/2018
1Warfarin (Coumadin)FDA LinkGeneric
01/2018
1DabigatranFDA Link
01/2018
1EnzymesIBA
12/2017
1FluoroquinolonesIBA
12/2017
1astaxanthine (astaxanthin)IBA
09/2017
1AntistaxIBA
09/2017
1Pain-FreeIBA
10/2016
1AcidsIBA
10/2016
1Biomarkers (Surrogate Marker)IBA
10/2016
1Retinaldehyde (Retinal)IBA
09/2015
1RobuvitIBA
06/2015
15,11-methenyltetrahydrohomofolateIBA
12/2014
1Dexamethasone (Maxidex)FDA LinkGeneric
11/2013
1Bendamustine HydrochlorideFDA Link
11/2013
1Bortezomib (Velcade)FDA Link
11/2013
1Albuterol (Salbutamol)FDA LinkGeneric
09/2011
1CollagenIBA
09/2011
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
09/2011
1Fluticasone (Cutivate)FDA LinkGeneric
09/2011
1Dust (House Dust)FDA Link
09/2011
1Polytetrafluoroethylene (Teflon)FDA Link
09/2011
1Pharmaceutical PreparationsIBA
09/2011
1Dihydrotachysterol (AT 10)IBA
09/2011
1SilverIBA
06/2010
1Phosphatidylcholines (Phosphatidylcholine)IBA
06/2010

Therapy/Procedure

8Therapeutics
01/2018 - 01/2000
2Drug Therapy (Chemotherapy)
12/2017 - 09/2017
2Compression Stockings
09/2011 - 09/2010
2Lasers (Laser)
11/2005 - 03/2005
1Immunotherapy
09/2017
1Radiotherapy
09/2017
1Sclerotherapy
09/2011
1Sutures (Suture)
09/2011